Carlo Rodolfo        

Curriculum Vitae.

Born in Vigevano (PV), February 12, 1967
Researcher, Department of Biology, University of Rome “Tor Vergata”.

Education.
- 2000 PhD in Cellular and Molecular Biology, University of Rome Tor Vergata
- 1992 Master Degree in Biology, University of Pavia

Doctoral and Post-Doctoral training.
- 2000-2002: Post-Doc in the group of Prof M. Piacentini, Department of Biology University of Rome “Tor Vergata”. Fellowship from the “European Community 5th Framework-Biotechnology Project”.
- April-June 2001: Visiting Fellow in the group of Prof. G. Kroemer, Institut Goustave Roussy, Villejuif, France. Supported by a fellowship from “Protein Cross-linking” The ESF Transglutaminases program”.
- 1998-2000: PhD Student in Cellular and Molecular Biology, University of Rome Tor Vergata.
- 1997-1998: Fellow in the group of Prof M. Piacentini, Department of Biology University of Rome Tor Vergata, Rome, Italy. Fellowship from the “European Community 5th Framework-Biotechnology Project”.
- Sept-Dec 1996: Visiting Fellow in the group of Prof. J.M. Egly, Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC), Strasbourg, France. Supported by a fellowship from the “EC Concerted Action on DNA Repair and Cancer”.
- 1995-1996: Fellowship from Fondazione Adriano Buzzati-Traverso, in the group of Dr. A. M. Pedrini, at the IGBE-CNR, Pavia.
- 1993-1995: Graduate fellow at the Istituto di Genetica e Biologia Evoluzionistica del CNR (IGBE-CNR, now Istituto di Genetica Molecolare, IGM-CNR), Pavia. Working on DNA damage and repair.

Teaching activities.
- Since 2012/13: Assistant Professor of Cytology and Histology (9 CFU), First Level Degree in Biology, Tuscia University, Viterbo.
- Since 2005/06: Assistant Professor of Cytology and Histology (5+1 CFU), First Level Degree in Biotechnology, University of Rome “Tor Vergata”, Rome.
- August 2009: Member of the Final Thesis defence committee for the “Master International en Technologies Biomédicales”, European community project TEMPUS JEP34020-2006 (MA), Al Akhawayn University, Ifrane, Morocco.
- October 2008: Lecturer at the “Master International en Technologies Biomédicales”, European community project TEMPUS JEP34020-2006 (MA), Al Akhawayn University, Ifrane, Morocco.
- Since 2008: Lecturer of Molecular Toxicology and Molecular Biology, IFTS and ITS courses.
- June 2005: Lecturer “1st Course on Molecular and Cellular Basis of Programmed Cell Death”, Universidad de La Habana, Cuba.
- 2004/05: Assistant Professor of Histology (3+2 CFU), First Level Degree in Biotechnology, University of Rome “Tor Vergata”, Rome.
- 2004/05: Assistant Professor of “Cell Death”, in the course “Cell Death and Differentiation”, Master Degree in Cell and Molecular Biology, University of Rome “Tor Vergata”, Rome.
- 2000/01-2004/05: Laboratory Assistant for the course of Cytology and Histology (5+2 CFU), Master Degree in Biology, University of Rome “Tor Vergata”, Rome.
- AA 1998/99-2004/05: Lecture (2 hours) “Gene Expression Regulation” for the Biology of Development course, Master Degree in Biology and Master Degree in Biotechnology, University of Rome “Tor Vergata”, Rome.

Awards.
- 1998. Award from Fondazione Adriano Buzzati-Traverso for his work on the “Characterisation of Tissue Transglutaminase from Danio rerio”.
- 2011. Award as Top Reviewer for Neuroscience.

Editorial activities.
- Since 2012. Editorial Board of ISRN Biochemistry-Hindawi Publishing Corporation
- Serves as Reviewer for: Experimental Cell Research, European Journal of Cell Biology, Journal of Cell Science, Biochemical Pharmacology, Cell Death and Differentiation, Cell Death and Disease, FEBS Letters, European Journal of Biochemistry, Neuroscience, Journal of Cellular Biochemistry, Neurochemistry International, Journal of Histochemistry & Cytochemistry.

Fields of study
Studying the role of Transglutaminase 2 in:
- Programmed Cell Death;
- Mitochondrial physiology and homeostasis;
- Cancer and metastases onset and progression;
- Neurodegenerative Diseases onset and progression.

Selected Papers
- Nicoll, WS, Sacci, JB, Rodolfo, C, Di Giacomo, G, Piacentini, M, Holland, ZJ, Doerig, C, Hollingdale, MR, Lanar, DE (2011) Plasmodium falciparum liver stage antigen-1 is cross-linked by tissue transglutaminase. Malar J 10:14.
- Rodolfo, C, Ciccosanti, F, Di Giacomo, G, Piacentini, M, Fimia, GM. (2010) Proteomic analysis of mitochondrial dysfunction in neurodegenerative diseases. Expert Rev Proteomics 7 (4):519-42.
- Malorni, W, Farrace, MG, Matarrese, P, Tinari, A, Ciarlo, L, Mousavi-Shafaei, P, D’Eletto, M, Di Giacomo, G, Melino, G, Palmieri, L, Rodolfo, C, Piacentini, M (2009) The adenine nucleotide translocator 1 acts as a type 2 transglutaminase substrate: implications for mitochondrial-dependent apoptosis. Cell Death Differ. 16(11):1480-92.
- Di Giacomo, G, Lentini, A, Beninati, S, Piacentini, M, Rodolfo, C (2008) In vivo evaluation of type 2 transglutaminase contribution to the metastasis formation in melanoma. Amino Acids 36(4):717-724.
- Rodolfo, C, Falasca, L, Di Giacomo, G, Mastroberardino, PG, Piacentini, M (2008) More than two sides of a coin? How to detect the multiple activities of type 2 transglutaminase. Meth Enzymol 442:201-12.
- Malorni, W, Farrace, MG, Rodolfo, C, Piacentini, M. (2008) Type 2 transglutaminase in neurodegenerative diseases: the mitochondrial connection. Curr Pharm Des 14(3):278-88.
- Mastroberardino, PG, Farrace, MG, Viti, I, Pavone, F, Fimia, GM, Melino, G, Rodolfo, C, Piacentini, M. (2006) “Tissue” transglutaminase contributes to the formation of disulphide bridges in proteins of mitochondrial respiratory complexes. Biochim. Biophys. Acta 1757(9-10):1357-65.
- Rodolfo, C, Mormone, E, Matarrese, P, Ciccosanti, F, Farrace, MG, Garofano, E, Piredda, L, Fimia, GM, Malorni, W, Piacentini, M. (2004) Tissue transglutaminase is a multifunctional BH3-only protein. J. Biol. Chem. 279(52):54783-92.