Prof. Patrizia Aducci        

 
1975 Degree in Biological Sciences- University of Rome “La Sapienza”.
1981-1987 Research associate- University of Rome “La Sapienza”- Faculty Of Science.
1982-1983 Teaching fellow “Biochemistry of nutrition” and “Physiology of nutrition” in the Advanced School of Nutrition Science- University of Rome “La Sapienza”.
1987-1994 Associate professor of Plant Physiology- University of Rome “Tor Vergata”.
1991-1992 Teaching contract in “Crop Physiology”- University of Basilicata, Potenza- Faculty of Agriculture.
1994-present Full professor of Plant Physiology- University of Rome “Tor Vergata”.
1995-2004 Director of the Advanced School of Biotechnology- University of Rome “Tor Vergata”.
1997-2001 President of the Italian Society of Plant Physiology.
1997-2005 Director of Consorzio Interuniversitario “Biologia Molecolare delle Piante”.
2001-2004 President of the course of Biotechnology (I level degree)- University of Rome “Tor Vergata”.
2004-2012 Head of Department of Biology-University of Rome “Tor Vergata”
2007-2010 Member of National Committee for Biosafety, Biotechnology and Life Science.
2009-2013 vice-Rector for coordination and development of University Research.

Special awards
2005 Medaglia Accademia Nazionale delle Scienze detta dei XL per le Scienze Fisiche e Naturali per il 2004

TEACHING
Plant biochemistry and physiology: Degree Course in Pharmacy
Pharmaceutical applications of plant metabolites: Degree Course in Pharmacy
Natural compound metabolism and officinal plants: Degree Course in Industrial Biotechnology (Second Level).

SCIENTIFIC PRODUCTIVITY
Research activity of Prof Aducci is on the biochemistry and molecular biology of plants and on the mechanism of plant growth and its regulation .
She is author of 100 papers on high-ranking journals and 180 abstracts of International and National Congresses on the following research topics

RESEARCH TOPICS
a)role of fusicoccin: a phytotoxin, a plant regulator and a potential new therapeutic agent;
b) plant signal transduction. 14-3-3 proteins: role and regulation . Sugar sensing pathways;
c) study of interaction of 14-3-3 proteins with targets in plants and other organisms;
d) role and regulation of 14-3-3 isoforms in plants;
e)plant transport: plasmalemma H+-ATPase and its regulation;
f) MAP kinases in plants: identification and characterization of ZmMPK6, a MAPkinase from maize;
g)plant proteinases: purification, localization and biochemical and kinetic characterization of proteinases from different plants.

GRANTS:
EU Contract BRIDGE in the frame of T-project “Regeneration”.
EU EU-Contract BIO4-CT97-2275/CRAFTT in the frame of IV Project Biotechnology.
EU EU Contract INTAS-94-4358 in the frame of INTAS project.
Ministero Politiche Agricole e Forestali (MIPAF): Contract “Sviluppo di Tecnologie Avanzate applicate alle piante”, Contract in the frame of National Project “Plant Biotechnology”, Contract in the frame of National Project ECOPOM (Tecniche innovative per l’identificazione di marcatori molecolari associati alla tipicità del pomodoro campano).

Ministero dell’Istruzione , dell’Università e della Ricerca (MIUR): PRIN projects 1998, 2000,2003,2005,2007 (National Coordinator), FIRB 2001.

Contract Consorzio Agrital Ricerche in the frame of P.N.R. Biotecnologie Avanzate II Fase “Recombinant DNA technology in agriculture”.

Regione Lazio Project 2008 Convenzione per interventi riqualificazione e ammodernamento laboratori di Ricerca e acquisizione impianti e macchinari.

COLLABORATIONS (last 5 years)
Dr. A. Paiardini, Prof. Cutruzzolà Dipartimento di Scienze Biochimiche, Università degli Studi di Roma La Sapienza, Roma.
Prof. G. Cesareni, Dr. S. Panni Dipartimento di Biologia Università degli Studi di Roma”Tor Vergata”,Roma.
Dr P. Torreri Department of Cell Biology and Neuroscience, Istituto Superiore di Sanità, Roma.
Dr S. Melino Dipartimento di Scienze e Tecnologie Università degli Studi di Roma”Tor Vergata”, Roma.
Prof. M. Maffei Dipartimento di Scienze della Vita e Biologia dei Sistemi, Università degli Studi di Torino.
Prof. M.I. De Michelis Dipartimento di Biologia, Università degli Studi di Milano, Milano.
Prof. A. Moroni Dipartimento di Biologia and IBF-CNR, Università degli Studi di
Milano, Milano.
Prof. G. Thiel Institut für Botanik, Technische Universität Darmstadt, D-64287 Darmstadt, Germany.

SELECTED PUBLICATIONS
Paiardini A., Aducci P., Cervoni L., Cutruzzolà F., Di Lucente C., Janson G., Pascarella S., Rinaldo S., Visconti S., Camoni L. (2014). The Phytotoxin Fusicoccin Differently Regulates 14-3-3 Proteins Association to Mode III Targets IUBMB Life. DOI 10.1002/iub.1239, Published online in Wiley Online Library.
Camoni L., Visconti S. , Aducci P. (2013) Hypothesis Paper- The phytotoxin fusicoccin, a selective stabilizer of 14-3-3 interactions? IUBMB Life 65, 513-517.
Camoni L., Di Lucente C., Pallucca R., Visconti S., Aducci P. (2012) Binding of phosphatidic acid to 14-3-3 proteins hampers their ability to activate the plant plasma membrane H+-ATPase IUBMB Life 64(8), 710–716, August 2012.
Camoni L., Di Lucente C., Visconti S., Aducci P. (2011) The phytotoxin fusicoccin promotes platelet aggregation via 14-3-3–glycoprotein Ib-IX-V interaction1 Biochem. J. 436, 429–436.
Visconti S., Camoni L., Marra M., Aducci P. (2008) Role of the 14-3-3 C-terminal region in the interaction with the plasma membrane H+-ATPase. Plant Cell Physiol. 49(12), 1887-97.
Garufi A., Visconti S., Camoni L., Aducci P. 2007. Polyamines as physiological regulators of 14-3-3 interaction with the plant plasma membrane H+-ATPase Plant Cell Physiol. 48,434-440.
Camoni L., Marra M., Garufi A., Visconti S., Aducci P. 2006. The Maize Root Plasma Membrane H+-ATPase Is Regulated by a Sugar-Induced Transduction Pathway Plant Cell Physiol. 47, 743-747.
Sottocornola B., Visconti S., Orsi S., Gazzarrini S., Giacometti S., Olivari C., Camoni L., Aducci P., Marra M., Abenavoli A., Thiel G., Moroni A. 2006. The potassium channel KAT1 is activated by plant and animal 14-3-3 proteins. J Biol Chem. 281(47), 35735-41.
Lalle M., Visconti S., Marra M., Camoni L., Velasco R., Aducci P. 2005. ZmMPK6, a novel maize MAP kinase that interacts with 14-3-3 proteins Plant Molecular Biology 59, 713–722.
Giacometti S., Camoni L., Albumi C., Visconti S., De Michelis M.I., Aducci P. 2004. Role of tyrosine phosphorylation of 14-3-3 proteins in plant plasma-membrane H+-ATPase regulation. Plant Biology, 6, 422-431.
Visconti S. Camoni L., Fullone M.R., Lalle M., Marra M., Aducci P. 2003. Mutational analysis of the interaction between 14-3-3 proteins and plant plasma membrane H+-ATPase. The Journal of Biological Chemistry, 278, 8172-8178
Aducci P., Camoni L., Marra M., Visconti S. 2002. From cytosol to organelles: 14-3-3 proteins as multifunctional regulators of plant cell. IUBMB Life, 53, 49-55
Camoni L., Visconti S., Marra M. and Aducci P. 2001. Adenosine 5’-monophosphate inhibits the association of 14-3-3 proteins with the plant plasma membrane H+-ATPase. The Journal of Biological Chemistry 276, 31709-31712
Camoni L., Iori V., Marra M., Aducci P. (2000) “Phosphorylation-dependent interaction between plant plasma membrane H+-ATPase and 14.3.3 proteins.” The Journal of Biological Chemistry , 275, 9919-9923
M. Marra, C. Olivari, S. Visconti, C. Albumi, P. Aducci, M.I. De Michelis (2000) A phosphopeptide corresponding to the cytosolic stretch connecting transmembrane segments 8 and 9 of the plasma membrane H+ ATPase binds 14 3 3 proteins and inhibits fusicoccin induced activation of the H+ ATPase, Plant Biology, 2, 1-6.
Fuglsang A.T., Visconti S., Drumm K., Jahn T., Stensballe A., Mattei B., Jensen O.N., Aducci P., Palmgren M.G. (1999) 14-3-3 protein Binding to the Plasma Membrane H+-ATPase AHA2 Involves the Three C-terminal Residues Tyr946-Thr-Val and Requires Phosphorylation of Thr947” The Journal of Biological Chemistry, 274, 36774-36780.
Fullone M.R., Visconti S., Marra M., Fogliano V. and Aducci P. (1998) Fusicoccin effect on the in vitro interaction between plant 14.3.3. proteins and plasma membrane H+-ATPase. The Journal of Biological Chemistry, 273 (N.13), 7698-7702
Marra M., Ballio A., Battirossi P., Fogliano V., Fullone MR. , Slayman C.L. and Aducci P., (1995) The fungal H+-ATPase from Neurospora crassa reconstituted with fusicoccin receptors senses fusicoccin signal. Proc.Natl.Acad.Sci. (USA), 92,1599-1603.
Aducci P., Ballio A., Fogliano V., Fullone M.R., Marra M., Proietti N. (1993). Purification and photoaffinity labeling of fusicoccin receptors from maize. European Journal of Biochemistry, 214, 339-445.
Aducci P., Ballio A., Blein J.-P., Fullone M.R., Rossignol M., Scalla R. (1988). Functional reconstitution of a proton-translocating system responsive to fusicoccin. Proc.Natl.Acad.Sci. ,85 (21),7849-7851.(Washington DC, USA).

RESEARCH GROUP
Patrizia Aducci- Full Professor- aducci@uniroma2.it tel. +39 06 7259 4343
Lorenzo Camoni- Researcher- Camoni@uniroma2.it tel. +39 06 72594810
Sabina Visconti- Researcher – Visconti@uniroma2.it tel. +39 06 72594810
Carlo Muzi- PhDstudent – muzi.carlo@gmail.com
Francesca Orangis- Undergraduated student – forangis@yahoo.it