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φBO1E, a newly discovered lytic bacteriophage targeting carbapenemase-producing Klebsiella pneumoniae of the pandemic Clonal Group 258 clade II lineage
Marco Maria D’Andrea, Pasquale Marmo, Lucia Henrici De Angelis, Mattia Palmieri, Nagaia Ciacci, Gustavo Di Lallo, Elisa Demattè, Elisa Vannuccini, Pietro Lupetti, Gian Maria Rossolini & Maria Cristina Thaller The pandemic dissemination of KPC carbapenemase-producing Klebsiella pneumoniae (KPC-KP) represents a major public health problem, given their extensive multidrug resistance profiles and primary […]
Ecotoxicological Method with Marine Bacteria Vibrio anguillarum to Evaluate the Acute Toxicity of Environmental Contaminants
This work describes a new protocol to assess the ecotoxicity of pollutants, including emerging contaminants such as nanomaterials, using the marine bacterium Vibrio anguillarum. This method allows for the determination of the LC50, or mortality, the concentration that causes a 50% […]
Oreste Segatto (IFO Roma) 4/4/2017
Coupling catalytic inhibition of RTKs to their enhanced degradation: insights from cell regulation and tentative design of rationale-based cancer therapies
Università di Tor Vergata