Carla Jodice     

CURRICULUM VITAE

EDUCATION AND TRAINING
1980 – Degree (Laurea) in Biological Sciences (110/110 cum laude), University “La Sapienza”, Rome, Italy.
1980 – 1985 – ReasearchFellow in Human and Population Genetics. Department of Genetics and Molecular Biology, University “La Sapienza” Rome, Italy.

EMPLOYMENT AND RESEARCH EXPERIENCE
2001 to present – Associate Professor of Genetics.Department of Biology, “Tor Vergata” University, Rome, Italy.
2005 – 2012 – ElectedMember of the ScientificBoard, “Centro Interuniversitario di Ricerca sulle Basi Molecolari delle Malattie Neurodegenerative”.
1989 – 2001 – Assistant Professor of Genetics. Human and Population Genetics.Department of Biology, “Tor Vergata” University, Rome, Italy.
1995 to present – Lecturer in Population Genetics within the Biological Science Undergraduate Program of the “Tor Vergata” University, Rome, Italy.
July 1998 – Department of Genetics, Stanford University, CA, USA. Research visitor. Human Genetics
1987 – 1997 – Assistant editor to the scientific journal Gene Geography published by the University of Tor Vergata, Rome, Italy.
July – Aug 1996 – Research visitor. Human Genetics.Lawrence Livermore National Laboratory, Livermore, CA, USA.
Feb – March 1993 – Expert on behalf of the Italian Ministry of Foreign Affairs to set up a Medical Genetics Laboratory at the University of Mansoura (Egypt) as part of a collaborative project between Italy and Egypt.
June 1990 – Research visitor. Human Genetics.In collaboration with Dr. Huda Zoghbi.Department of Molecular Genetics, University of Texas, Houston, USA.
1987 – 1988 – Postdoctoral fellow. Human and Population Genetics.Population Genetics laboratory, Department of Biology, “Tor Vergata” University, Rome, Italy.
1985 – 1986 -Fellowship recipient. Human Genetics. Department of Human Genetics, Leiden University, The Netherlands. Laboratory directed by Prof. Luigi F. Bernini.

MAJOR RESEARCH INTERESTS
• Research on genotypic/phenotypic variability of autosomal dominant cerebellar ataxias.
• Genetic and physical mapping of genetic diseases by means of highly polymorphic DNA markers.
• Population and evolutionary studies of human mtDNA and Y chromosome.
• Research on human genetic variability as revealed by protein and DNA polymorphisms.

RESEARCH FUNDING
She had been national scientific coordinator (in 2003) and local scientific coordinator (in 2005 and 2007) of two-yearprojects financed by Italian University and Research Ministry(MIUR) within the Scientific Research Programs of National Interest “(PRIN); furthermore she has participated in several projects financed by CNR and UE.

PUBLICATIONS
She is author or co-author of more than 40 publications on international peer-reviewed journals and/or requested reviews. The 5 most significant publications of the last decade are:
DE CHIARA C, GIANNINI C, ADINOLFI S, DE BOER J, GUIDA S, RAMOS A, JODICE C, KIOUSSIS D, PASTORE A. (2003) The AXH module: an independently folded domain common to ataxin-1 and HBP1. FEBS Lett. 551, 107-112.
MANTUANO E, VENEZIANO L, SPADARO M, GIUNTI P, GUIDA S, LEGGIO MG, VERRIELLO L, WOOD N, JODICE C, FRONTALI M. (2004) Clusters of non-truncating mutations of P/Q type Ca2+ channel subunit CaV2.1 causing Episodic Ataxia 2. J Med Genet.41, e82.
VENEZIANO L, GUIDA S, MANTUANO E, BERNARD P, TARANTINO P, BOCCONE L, HISAMA FM, CARRERA P, JODICE C, FRONTALI M (2009) Newly characterised 5′ and 3′ regions of CACNA1A gene harbour mutations associated with Familial Hemiplegic Migraine and Episodic Ataxia. J Neurol Sci. 276, 31-37.
VENEZIANO L, ALBERTOSI S, PESCI D, MANTUANO E, FRONTALI M, JODICE C. (2011) Dramatically different levels of cacna1a gene expression between pre-weaning wild type and leaner mice. J Neurol Sci. 305, 71-74.
MAPELLI L, CANALE C, PESCI D, AVERAIMO S, GUIZZARDI F, FORTUNATI V, FALASCA L, PIACENTINI M, GLIOZZI A, RELINI A, MAZZANTI M, JODICE C. (2012) Toxic effects of expanded ataxin-1 involve mechanical instability of the nuclear membrane. BiochimBiophysActa. 1822, 906-917.

EDUCATIONAL ACTIVITIES
Since 1995 she taught courses in the fields of Human Genetics and Population Genetics for the First Level degree (laurea) courses in Human Biology, Cellular and Molecular Biology, Chemistry and Life Sciences, and for Master Degree (laureamagistrale) course in Biology and Human Evolution.
She is currently teaching Geneticsfor the First Level degree (laurea) courses in Life Sciences.
2004-today she is coordinator for the ERASMUS programme concerning mobility of students for the courses in Biological Sciences.