camoni 122x155Dr. Lorenzo Camoni     Bandiera-Tricolore-Italiana

Degree in Biology (1994), University of Rome “La Sapienza”. Research Fellow, University of Rome “La Sapienza” (1994-1995). Research Fellow (National Research Council, CNR), University of Rome “Tor Vergata” (1995-1997). Research Fellow, Institute of Molecular Biology, University of Copenhagen, Denmark (1998). Research Fellow (EU IV Framework Programme, University of Rome “Tor Vergata” (1998-2000). Research Scientist in Plant Physiology, SSD BIO/04 (2000).

Teaching activity
2001-today. Plant Biochemistry, Plant Physiology, Defense Responses in Plants, Plant Signal Transduction, Plant Functional Genomics, Photosynthesis and Environment, Plant Biochemistry and Molecular Biology.

Scientific activity
Purification, structure determination and biological activity of phytotoxic metabolites from the bacterium Pseudomonas syringae.
Molecular mechanism of plant plasma membrane H+-ATPase regulation. Mechanism of action of the fungal toxin fusicoccin. Purification and characterization of protein kinases/phosphatases involved in the 14-3-3-mediated H+-ATPase regulation.
Identification of novel fusicoccin molecular targets. Pharmacological activity of fusicoccin.

Funding
EU grant (Project of Tecnological Priority, 1997). Participation to several research projects (EU IV Framework Programme, Italian Ministry of Research and Education (MIUR), National Reseach Council (CNR), and Italian Ministry of Agricolture).

More
Member of the academic board of the PhD School in Cell and Molecular Biology, University of Rome “Tor Vergata”. Member (since 1998) of the Italian Society of Plant Biology (SIBV, formerly Italian Society of Plant Physiology). Member (since 1998) of the Federation of the European Societies of Plant Biology). Peer reviewer for the Italian Ministry of Research and Education (MIUR).Peer reviewer for scientific journals (Planta, Physiologia Plantarum, FEBS Letters).

Patents
The fungal phytotoxin fusicoccin for the treatment and diagnosis of coagulation-correlated pathologies. Inventors: Camoni, L., Di Lucente, C., Visconti, S and Aducci, P. Assignee: University of Rome “Tor Vergata”. Registered at the USA Pat
ent Office, 23/05/08, N° 12/126205. Approval date: 26/04/2011, N° US7932233B2.

Pubications
- Di Giorgio, D., Camoni, L. and Ballio, A. (1994). Toxins of Pseudomonas syringae pv. syringae affect H+-transport across the plasma membrane of maize. Physiologia Plantarum 91: 741-746.
- Camoni, L., Di Giorgio, D., Marra, M., Aducci, P. and Ballio, A. (1995). Pseudomonas syringae pv. syringae phytotoxins reversibly inhibit H+-ATPase and disrupt unilamellar liposomes. Biochemical and Biophysical Research Communications 214: 118-124.
- Ballio, A., Bossa, F., Camoni, L., Di Giorgio, D., Flamand, M.-C., Maraite, H., Nitti, G., Pucci, P.and Scaloni, A. (1996). Structure of fuscopeptins, phytotoxic metabolites of Pseudomonas fuscovaginae. FEBS Letters 381: 213-216.
- Di Giorgio, D., Lavermicocca, P., Marchiafava, C., Camoni, L., Surico, G. and Ballio, A. (1996). Effect of syringomycin-E and syringopeptins on isolated plant mitochondria. Physiological and Molecular Plant Pathology 48: 325-334.
- Di Giorgio, D., Camoni, L., Mott, K. A., Takemoto, J. Y. and Ballio, A. (1996). Syringopeptins, Pseudomonas syringae pv. syringae phytotoxins, resemble syringomycin in closing stomata. Plant Pathology 45: 564-571.
- Bachmann, R.C., Ballio A., Barra, D., Bossa, F., Camoni, L., Di Giorgio, D., Di Nola, A., Ferranti, P., Grgurina, I., Iacobellis, N.S., Lavermicocca, P., Manetti, C., Marchiafava, C., Marino, G., Mott, K.A., Paci, M., Pucci, P., Scaloni, A., Segre, A., Simmaco, M., Strobel, G.A., Surico, G. and Takemoto, J.Y. (1997). Lipodepsipeptides from Pseudomonas syringae pv. syringae. In Pseudomonas Syringae Pathovars and Related Pathogens (Rudolph, K., Burr, T. J., Masnfield, J. W., Stead, D., Vivian, A. and von Kietzell J. Eds.), pp. 170-175. Springer, Berlin.
- Lavermicocca, P., Ballio, A., Camoni, L., Di Giorgio, D. and Marchiafava, C. (1997). Studies on the effect of syringomycin and syringopeptins on the functions of plant mitochondria. In Pseudomonas Syringae Pathovars and Related Pathogens (Rudolph, K., Burr, T. J., Masnfield, J. W., Stead, D., Vivian, A. and von Kietzell J. Eds.), pp. 198-201. Springer, Berlin.
-Di Giorgio, D., Camoni, L., Scaloni, A., Scortichini, M. and Ballio, A. (1997). A new syringopeptin produced by a Pseudomonas syringae strain from laurel. In Pseudomonas Syringae Pathovars and Related Pathogens (Rudolph, K., Burr, T. J., Masnfield, J. W., Stead, D., Vivian, A. and von Kietzell J. Eds.), pp. 208-209. Springer, Berlin.
- Di Giorgio, D., Camoni, L., Marchiafava, C. and Ballio, A. (1997). Biological activities of Pseudomycin A, a lipodepsinonapeptide from Pseudomonas Syringae MSU 16H. Phytochemistry 45: 1385-1391.
- Scaloni, A., Camoni, L., Di Giorgio, D., Scortichini, M., Cozzolino, R. and Ballio, A. (1997). A new syringopeptin produced by a Pseudomonas syringae pv. syringae strain isolated from diseased twigs of laurel. Physiological and Molecular Plant Pathology 51: 259-264.
- Camoni, L., Harper, J.F., and Palmgren, M.G. (1998). 14-3-3 proteins activate a plant calcium-dependent protein kinase (CDPK). FEBS Letters 430: 381-384.
- Emanuele, M.C., Scaloni, A., Lavermicocca, P., Jacobellis, N.S., Camoni, L., Di Giorgio, D., Pucci, P., Paci, M., Segre, A., and Ballio, A. (1998). Corpeptins, new bioactive lipodepsipeptides from cultures of Pseudomonas corrugata. FEBS Letters 433: 317-320.
- Camoni, L., Fullone, M.R., Marra, M., and Aducci, P. (1998). The plasma membrane H+-ATPase from maize roots is phosphorylated on the C-terminal domain by a calcium-dependent protein kinase. Physiologia Plantarum 104: 549-555. Copenhagen, Denmark.
- Camoni, L., Iori, V., Marra, M., and Aducci, P. (2000). Phosphorylation-dependent interaction between plant plasma membrane H+-ATPase and 14-3-3 proteins. The Journal of Biological Chemistry 275: 9919-9923.
- Camoni, L., Visconti, S., Marra, M., and Aducci, P. (2001). Adenosine 5′-monophosphate inhibits the association of 14-3-3 proteins with the plant plasma membrane H+-ATPase. The Journal of Biological Chemistry 276: 31709-31712.
- Aducci, P., Camoni, L., Marra, M., and Visconti, S. (2002). From cytosol to organelles: 14-3-3 proteins as multifunctional regulators of plant cell. IUBMB Life 53: 49-55.
- Visconti, S., Camoni, L., Fullone, M.R., Lalle, M., Marra, M., and Aducci, P. (2003) Mutational analysis of the interaction between 14-3-3 proteins and plant plasma membrane H+-ATPase. The Journal of Biological Chemistry 278: 8172-8178.
- Aducci, P., Camoni, L., Fullone, M.R., Marra, M., and Visconti, S. (2003). Fusicoccin: Phytotoxin or molecular signal? In Bacterial, Plant and Animal Toxins, 2003. (Ascenzi, P., Ponticelli, F.and Visca, P. Eds.), pp. 59-67. Research Signpost, Trivandrum, India.
- Giacometti, S., Camoni, L., Albumi, C., Visconti, S., De Michelis, M. I., and Aducci, P. (2004). Tyrosine phosphorylation inhibits the interaction of 14-3-3 proteins with the plant plasma membrane H+-ATPase. Plant Biology 6: 422-431.
- Lalle, M., Visconti, S., Marra, M., Camoni, L., Velasco, R, and Aducci, P. (2005). ZmMPK6, a novel maize MAP kinase that interacts with 14-3-3 proteins. Plant Molecular Biology 59: 711-720.
- Camoni, L., Marra, M., Garufi, A., Visconti, S., and Aducci, P. (2006) The Maize Root Plasma Membrane H+-ATPase is Regulated by a Sugar-induced Transduction Pathway. Plant Cell Physiology 47: 743-747.
- Sottocornola, B., Visconti, S., Orsi, S., Gazzarrini, S., Giacometti, S., Olivari, C., Camoni, L., Aducci, P., Marra, M., Abenavoli, A., Thiel, G., and Moroni, A. (2006) The potassium channel KAT1 is activated by plant and animal 14-3-3 proteins. The Journal of Biological Chemistry 281: 35735-35741.
- Garufi, A., Visconti, S., Camoni, L., and Aducci, P (2007). Polyamines as physiological regulators of 14-3-3 interaction with the plant plasma membrane H+-ATPase. Plant Cell Physiology 48: 434-440. Kyoto, Japan.
- Visconti, S., Camoni, L., Marra, M.,and Aducci P. (2008) Role of the 14-3-3 C-terminal region in the interaction with the plasma membrane H+-ATPase. Plant Cell Physiology 49: 1887-1897.
- Camoni, L., Di Lucente, C., Visconti, S., and Aducci, P. (2011) The phytotoxin fusicoccin promotes platelet aggregation via 14-3-3-glycoprotein Ib-IX-V interaction. The Biochemical Journal 436: 429-436.
- Camoni, L., Di Lucente, C., Pallucca, R., Visconti, S., and Aducci, P. (2012) Binding of phosphatidic acid to 14-3-3 proteins hampers their ability to activate the plant plasma membrane H+-ATPase. IUBMB Life 64: 710-716.
- Camoni, L., Visconti, S., and Aducci, P. (2013) The phytotoxin fusicoccin, a selective stabilizer of 14-3-3 interactions? IUBMB Life 65: 513-517.
- Paiardini, A., Aducci, P., Cervoni, L., Cutruzzolà, F., Di Lucente, C., Janson, G., Pascarella, S., Rinaldo, S., Visconti, S., and Camoni, L. (2014) The phytotoxin fusicoccin differently regulates 14-3-3 proteins association to mode III targets. IUBMB Life. doi: 10.1002/iub.1239.